Pim-1

These data identify Pim-1 as a critical regulator of LN pathogenesis and targeting Pim-1/NFATc1/NLRP3 pathway might be a therapy for human LN.

https://www.ncbi.nlm.nih.gov/pubmed/30791224?dopt=Abstract

https://onlinelibrary.wiley.com/doi/abs/10.1002/art.40863

[Read more…] about Pim-1 as a therapeutic target in human lupus nephritis – “targeting Pim-1/NFATc1/NLRP3 pathway might be a therapy for human lupus nephritis … mice were used to confirm the therapeutic effects of Pim-1 inhibition”